Consumption of Very Low Mineral Water Is Associated with Lower Bone Mineral Content in Children

Yujing Huang1, Xiangyu Ma2, Yao Tan1

  • 1Department of Environmental Hygiene, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, China.

Insights

Consuming very low mineral water may negatively impact children's bone health and growth. This water was linked to reduced bone mineral content and height, alongside increased bone resorption, highlighting potential health risks.

Area of Science:

  • Pediatric Nutrition
  • Bone Biology
  • Public Health

Background:

  • Previous research indicated very low mineral drinking water may hinder schoolchildren's height development.
  • The specific impact of such water on bone modeling processes in children was previously unknown.

Purpose of the Study:

  • To investigate the effects of very low mineral water consumption on bone modeling biomarkers in children.
  • To assess the association between drinking water mineral content and indicators of bone health.

Main Methods:

  • A 4-year retrospective cohort study compared children aged 10-13 consuming normal mineral water (NW) versus very low mineral water (VLW).
  • Evaluated differences in daily mineral intake, growth parameters, and serum biomarkers for osteoblast activity, bone formation, and resorption.
  • Utilized independent t-tests, chi-square tests, multiple linear regression, and binary logistic regression for analysis.

Main Results:

  • The VLW group exhibited lower daily calcium intake, reduced height increase, and decreased bone mineral content (BMC) compared to the NW group.
  • VLW consumption was associated with lower osteoblast activity (serum bone alkaline phosphatase - BALP) and higher bone resorption (serum CTX).
  • Calcium intake from drinking water positively correlated with height increase, BMC, and BALP, while negatively correlating with CTX.

Conclusions:

  • Very low mineral water consumption may lead to osteoblast inhibition, increased bone resorption, reduced bone mineral density, and retarded growth in children.
  • The potential health risks associated with very low mineral water intake in pediatric populations warrant consideration.
Abstract

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