Related Experiment Video
Updated: Jan 21, 2026
06:26
Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI
Published on: November 27, 2019
77.3K
Neural activity during working memory encoding, maintenance, and retrieval: A network-based model and meta-analysis.
1Department of Rehabilitation Psychology, Daegu University, Gyeongsan-si, Republic of Korea.
Human Brain Mapping
|August 3, 2019
Summary
Working memory (WM) involves distinct brain networks for encoding, maintenance, and retrieval. The dorsal attention network (DAN) is key for encoding, while the frontoparietal control network (FPCN) is crucial for later stages.
Area of Science:
- Cognitive Neuroscience
- Neuroimaging
Background:
- Working memory (WM) involves temporal subprocesses: encoding, maintenance, and retrieval.
- The specific intrinsic brain networks underlying these WM phases remain unclear.
Purpose of the Study:
- To model and validate the distinct intrinsic network contributions to WM temporal subprocesses.
- To clarify the roles of the dorsal attention network (DAN) and frontoparietal control network (FPCN) in WM phases.
Main Methods:
- Construction of a computational model of intrinsic network involvement in WM phases.
- Quantitative meta-analysis of functional neuroimaging data to test the model's predictions.
- Between-phase contrasts to identify double dissociations between networks and WM stages.
Main Results:
- Model suggests decreasing DAN involvement and increasing FPCN involvement from encoding to retrieval.
- Meta-analysis confirmed phase-specific network contributions, with double dissociations observed.
- Distinct functional roles for closely located DAN and FPCN regions were identified.
Conclusions:
- WM temporal subprocesses are supported by distinct, dynamically interacting intrinsic networks.
- The DAN is primarily involved in WM encoding, while the FPCN is critical for maintenance and retrieval.
- This study refines our understanding of WM network organization and functional specialization.
Related Concept Videos
01:29Self-Evaluation Maintenance Model
291
The Self-Evaluation Maintenance (SEM) model offers a psychological framework to understand how individuals’ self-esteem is influenced by the achievements of others, particularly those with whom they share close personal bonds. The SEM model operates when personal rather than social identity guides individuals. Central to this model is the notion that individuals have an inherent desire to preserve a favorable self-image, which is continuously shaped by interpersonal comparisons and...
291
01:12Retrieval
422
Retrieval is the process of getting information out of memory storage and back into conscious awareness. This ability is essential for daily tasks like brushing hair and teeth, driving to work, and performing job duties. Retrieval occurs in three ways: recall, recognition, and relearning.
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
422
01:19Encoding
767
Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
767
01:45ER Retrieval Pathway
4.7K
In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...
4.7K
02:26Protein Networks
4.5K
An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
4.5K
01:09Directing Effect of Substituents: meta-Directing Groups
5.8K
Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
5.8K