Related Experiment Video
Updated: Jan 21, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
Published on: October 10, 2025
Neurofibromatosis type 1 with tarsal conjunctiva thickening: A case report
Joo Young Kim1, Mee Yon Lee, Young Chun Lee
1Department of Ophthalmology, Uijeongbu St Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Rationale:
We report a rare case of neurofibroma in the form of tarsal conjunctival thickening of the eyelid in patients with neurofibromatosis type 1 (NF1), common ocular complications of which are Lisch nodules, choroidal nodules, and optic nerve glioma.
Patient Concerns:
A 46-year-old female patient was diagnosed with neurofibroma after biopsy and removal of 2 lumbar level intradural masses 15 years ago. She was being monitored without recurrence. When the patient visited our hospital, multiple iris Lisch nodules were found in both her eyes with ill-defined, diffuse thickening in the upper eyelid tarsal conjunctiva of the right eye.
Diagnosis:
Neurofibroma was diagnosed by incisional biopsy and immunohistochemistry of the tarsal conjunctiva.
Interventions:
The patient of the present case did not undergo any additional surgical treatment because tarsal conjunctiva thickening caused little functional problem.
Outcomes:
The patient has only been regularly examined for changes in size of neurofibroma, and there was no change in size over a 12-month period.
Lessons:
Neurofibroma should be considered as a differential diagnosis if a patient diagnosed with NF1 shows tarsal conjunctiva thickening.
Related Concept Videos
Types of Reports I: Hands-off Report
Following are the key components and categories of hand-off reports:
Purpose and Process:
Types of Reports II: Incident or Occurrence Report
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Types of Reports III: Telephone and Verbal Reports
Here's an overview of each type:
Telephone Orders
Data Reporting and Recording
Reporter Genes
Types of RNA
Three main types of RNA are involved in protein synthesis: messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA). These RNAs perform diverse functions and can be broadly classified as protein-coding or non-coding RNA. Non-coding RNAs play important roles in the regulation of gene expression in response to developmental and environmental changes. Non-coding RNAs in prokaryotes can be manipulated to develop more effective antibacterial drugs for human or animal use.
RNA...

