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Clinical Analysis of Pediatric Thyroid Cancer: A Single Medical Institution Experience of 18 Years

Hyung Kwon Byeon1, Sang Bin Kim1, Hyeon Seok Oh1

  • 1Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

The Annals of Otology, Rhinology, and Laryngology
|August 4, 2019
PubMed

Insights

Pediatric thyroid cancer, though rare, has distinct characteristics. Key recurrence factors include age, tumor size, and lymph node metastasis, guiding tailored treatment for better outcomes.

Area of Science:

  • Endocrinology
  • Pediatric Oncology
  • Surgical Oncology

Background:

  • Pediatric thyroid cancer incidence is significantly lower than in adults.
  • Thyroid cancer in children presents unique clinical and pathological features.

Purpose of the Study:

  • To analyze institutional data on pediatric thyroid cancer.
  • To identify risk factors for recurrence and evaluate treatment outcomes in young patients.

Main Methods:

  • Retrospective review of 83 patients under 20 diagnosed with thyroid carcinoma between 2000-2018.
  • Primary treatment involved surgery at a high-volume tertiary center.

Main Results:

  • Papillary thyroid carcinoma (PTC) was most common (74/83).
  • Tumor size >1cm correlated with increased lymph node metastasis and extrathyroidal extension.
  • Age, tumor size, multifocality, lateral lymph node metastasis, and postoperative thyroglobulin levels predicted recurrence.

Conclusions:

  • Pediatric thyroid cancer is a distinct entity requiring specific consideration.
  • Several prognostic factors can guide risk stratification and management strategies.
Abstract

Keywords:
papillary thyroid carcinomapediatric thyroid cancerrecurrence

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