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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
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Primary bronchial Ewing sarcoma.
Hamid Mumtaz1, Farah Khalil1, Amit Tandon1
1Moffitt Cancer Center, 12902 USF Magnolia Drive, Tampa, FL, 33612, USA.
International Journal of Surgery Case Reports
|August 5, 2019
Summary
Primary bronchial Ewing sarcoma (ES) is rare. This case shows limited resection with sleeve surgery can be a safe and effective treatment for bronchial ES, avoiding adjuvant therapy.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Oncology
Background:
- Primary bronchial Ewing sarcoma (ES) is an exceptionally rare endobronchial tumor.
- Ewing sarcoma typically affects bone and soft tissues, with bronchial involvement being exceedingly uncommon.
Purpose of the Study:
- To present a case of primary bronchial Ewing sarcoma.
- To evaluate the efficacy and safety of limited surgical resection for this rare condition.
- To compare the prognosis of bronchial ES with other locations.
Main Methods:
- A 65-year-old male with progressive dyspnea underwent flexible bronchoscopy, revealing an endobronchial polypoid tumor.
- The tumor was successfully resected using a left bronchial sleeve resection via thoracotomy.
- Pathological analysis confirmed complete tumor resection with negative margins and features consistent with ES.
Main Results:
- The patient experienced an uneventful recovery post-surgery.
- No adjuvant radiation or chemotherapy was administered.
- The patient remained disease-free at a 9-month follow-up.
- Literature review identified limited cases of bronchial, tracheal, and lung parenchyma ES.
Conclusions:
- Primary bronchial ES has a potentially better prognosis compared to tracheal or lung parenchymal ES.
- Limited resection, such as sleeve resection, can be a safe and effective treatment for primary bronchial ES.
- Achieving negative margins may obviate the need for adjuvant therapy in select cases of bronchial ES.
Keywords:
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