Multi-level Intervention Program - A Quality Improvement Initiative to Decrease Central Line-Associated Bloodstream

Karla Marie Bathan Santos1, Sufia S Husain2, Vanessa Torres3

  • 1UCLA School of Nursing, Los Angeles, CA, United States of America.

Insights

Implementing an intervention significantly reduced central line-associated bloodstream infections (CLABSIs) in pediatric patients. While staff adherence was high, parent adherence was low, highlighting a need for targeted parent education to further prevent CLABSIs.

Area of Science:

  • Pediatric Healthcare
  • Infection Prevention and Control
  • Clinical Interventions

Background:

  • Central venous catheters (CVCs) are essential for pediatric patients requiring long-term intravenous therapy.
  • CVC use increases the risk of central line-associated bloodstream infections (CLABSIs).
  • Effective infection control strategies are crucial in pediatric care settings.

Purpose of the Study:

  • To evaluate adherence to intervention components aimed at reducing CLABSIs in pediatric units.
  • To assess the impact of the intervention on CLABSI rates over a five-year period.
  • To identify factors influencing adherence and infection rates.

Main Methods:

  • A multi-component intervention was implemented across pediatric acute care and hematology-oncology units.
  • Adherence was monitored using a CVC audit sheet.
  • CLABSI rates were collected quarterly for five years, comparing pre- and post-intervention periods.

Main Results:

  • CLABSI rates demonstrated a steady decrease over the five-year study period.
  • Staff adherence to intervention components ranged from 90% to 100%, with lowest adherence to patient protective equipment (PPE).
  • Hospital-acquired CLABSIs decreased from 41 incidents pre-intervention to 9 incidents post-intervention.

Conclusions:

  • The intervention was effective in reducing CLABSI rates in pediatric units.
  • Sustained high staff adherence is critical for infection prevention.
  • Low parent/family adherence necessitates targeted strategies, including enhanced education and visible reminders for PPE compliance.
Abstract

Related Concept Videos

Initiation of Translation02:33

Initiation of Translation

Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
38.4K
Initiation of Translation02:33

Initiation of Translation

7.9K
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
1.0K
Decreased pulse rate01:14

Decreased pulse rate

Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
854
Nursing Interventions I: Taxonomy of Nursing Interventions01:03

Nursing Interventions I: Taxonomy of Nursing Interventions

Nursing interventions are chosen as part of the planning process to achieve patient outcomes. Once nursing diagnoses are determined, the goals and outcomes are specified, then the nursing interventions are selected and individualized according to the patient's situation.
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
3.6K
Nursing Interventions II: Selecting and Classifying the Nursing Interventions01:29

Nursing Interventions II: Selecting and Classifying the Nursing Interventions

Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
3.1K