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Updated: Jan 21, 2026

Author Spotlight: Magnetometric Characterization of Intermediates in the Solid-State Electrochemistry of Redox-Active Metal-Organic Frameworks
Published on: June 9, 2023
Metal-organic framework-1210(zirconium/cuprum) modified magnetic nanoparticles for solid phase extraction of
Wenqing Li1, Rong Wang1, Zilin Chen1
1Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, China; State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Beijing, 10080, China.
Abstract:
MOF-1210(Zr/Cu) is a new heterometallic cluster-based metal-organic framework material as well as a promising solid phase extraction coating material with ordered spatial structure, permanent high porosity and large specific surface area. In this work, a novel MOF-1210(Zr/Cu) modified magnetic nanoparticles (MNPs) was successfully prepared for magnetic solid phase extraction (MSPE) of benzophenones, including 2,4-dihydroxybenzophenone (BP-1), 2-hydroxy-4-methoxybenzophenone (BP-3) and 2,2',4,4'-tetrehydroxybenzophenone (BP-6). The MOF-1210(Zr/Cu)-MNPs were synthesized in one step by a simple solvothermal method and showed high extraction efficiency towards analytes (with enrichment factors of 91-122). The extraction mechanism studies showed that the hydrogen bond interaction and coordination interaction between MOF-1210(Zr/Cu) and BPs played important roles during the extraction process. By coupling with HPLC, the MOF-1210(Zr/Cu)-MNPs-based MSPE-HPLC method showed wide linear range (0.1-300.0 ng·mL-1), good linearity (R ≥ 0.9982), excellent reproducibility (RSD ≤ 3.60%) and remarkable sensitivity (LODs in the range of 0.01-0.02 ng·mL-1). This method was also successfully applied to the extraction and detection of benzophenones in soil samples. Good recoveries were obtained (87.6%-113.8%) with RSDs less than 11.12%, which demonstrated the practicality of the proposed method.
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