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Updated: Jan 21, 2026
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Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
Published on: February 27, 2015
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Masson tumor as a neck mass
M Alotaibi1, V Geisler1, H Olze1
1Department of Otorhinolaryngology, Head and Neck Surgery, Charité - University Medical Center Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.
Summary
Masson's tumor, a benign intravascular papillary endothelial hyperplasia (IPEH), is rare in the neck. Surgical excision is effective, with no recurrence observed in this case.
Area of Science:
- Vascular Pathology
- Surgical Oncology
Background:
- Masson's tumor, or intravascular papillary endothelial hyperplasia (IPEH), is a benign intravascular neoplasm.
- Histologically, it features papillary endothelial projections within a vessel lumen, associated with thrombi.
- CD 31 and CD 34 immunohistochemistry aid in identifying vascular origin.
Observation:
- A 54-year-old male presented with a 3-week history of a right lateral neck mass.
- CT revealed a 20mm×9mm cystic mass with a draining vessel.
- Surgical excision and subsequent pathology confirmed a thrombosed vein with papillary structure.
Findings:
- The resected mass showed features consistent with Masson's tumor (IPEH).
- No evidence of atypia, necrosis, or perivascular invasion was noted.
- The patient experienced an uncomplicated recovery with no recurrence at 8 months.
Implications:
- IPEH can be distinguished from angiosarcoma by the absence of atypia, necrosis, and perivascular extension.
- Surgical excision is the recommended treatment for Masson's tumor.
- This case highlights an unusual presentation of Masson's tumor in the neck.
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