Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coordination Number and Geometry02:57

Coordination Number and Geometry

18.9K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
18.9K
Nucleotide Excision Repair01:08

Nucleotide Excision Repair

40.6K
Overview
40.6K
Nucleotide Excision Repair01:38

Nucleotide Excision Repair

5.0K
DNA Distortion and Damage
Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...
5.0K
Polymers02:34

Polymers

40.5K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
40.5K
Coordination Compounds and Nomenclature02:54

Coordination Compounds and Nomenclature

26.4K
In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
26.4K
Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

11.4K
The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
11.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ordering-Driven Biaxial Strain Engineering in PtNi Intermetallic Nanowires for Oxygen Reduction Catalysis.

Angewandte Chemie (International ed. in English)·2026
Same author

Guanine-Rich DNA Aptamers for Selective Binding to Agarose Hydrogels.

Bioconjugate chemistry·2026
Same author

Capture-SELEX-Derived Low-Nanomolar-Affinity Aptamers for Doxorubicin and Inhibition of Cellular Uptake.

ACS chemical biology·2026
Same author

Enzymes, DNAzymes and nanozymes for environmental remediation.

Nanoscale·2026
Same author

LPI alleviates Alzheimer's disease pathology via the GPR55 receptor.

Neuroscience·2026
Same author

Combining G-Quadruplex and Non-Quadruplex Aptamers with Distinct Thermodynamic Driving Forces for Highly Selective Pb<sup>2+</sup> Detection.

ACS sensors·2026

Related Experiment Video

Updated: Jan 21, 2026

Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
10:27

Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides

Published on: July 14, 2015

10.5K

Growing a Nucleotide/Lanthanide Coordination Polymer Shell on Liposomes.

Yibo Liu1, Juewen Liu1

  • 1Department of Chemistry, Waterloo Institute for Nanotechnology , University of Waterloo , Waterloo , Ontario N2L 3G1 , Canada.

Langmuir : the ACS Journal of Surfaces and Colloids
|August 6, 2019
PubMed
Summary

Researchers developed a novel gadolinium/adenosine monophosphate (Gd3+/AMP) shell coating for liposomes. This nanoparticle shell enhances liposome stability and prevents leakage, offering a simple method for improved liposome formulation.

More Related Videos

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
13:51

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

15.8K
Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
13:21

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Published on: July 21, 2011

15.3K

Related Experiment Videos

Last Updated: Jan 21, 2026

Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides
10:27

Preparation of Highly Porous Coordination Polymer Coatings on Macroporous Polymer Monoliths for Enhanced Enrichment of Phosphopeptides

Published on: July 14, 2015

10.5K
Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
13:51

Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications

Published on: November 10, 2017

15.8K
Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
13:21

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging

Published on: July 21, 2011

15.3K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Biochemistry

Background:

  • Liposome shells enhance membrane stability, preventing leakage and fusion.
  • Lanthanide coordination nanoparticles (NPs) form via simple ambient mixing.
  • Lipid headgroups with lanthanide-binding ligands can direct NP growth.

Purpose of the Study:

  • To form a gadolinium/adenosine monophosphate (Gd3+/AMP) shell on liposomes.
  • To investigate the effect of lipid headgroups on shell formation.
  • To evaluate the stability and protective properties of the liposome@Gd3+/AMP system.

Main Methods:

  • Formation of Gd3+/AMP shell on liposomes with phosphoserine (PS) and cholinephosphate (CP) headgroups.
  • Transmission electron microscopy (TEM) for visualizing liposome binding and shell formation.
  • Surface charge analysis and leakage assays using Triton X-100 and ZnO NPs.

Main Results:

  • Gd3+/AMP shell successfully formed on PS and CP liposomes, but not phosphocholine liposomes.
  • Gd3+ binding reversed the negative surface charge of PS and CP liposomes.
  • The Gd3+/AMP shell protected liposomes from ZnO NP-induced leakage, indicating a porous structure.

Conclusions:

  • A facile method for coating liposomes with a Gd3+/AMP shell was established.
  • Liposome adsorption of lanthanide ions and subsequent shell formation were understood.
  • The developed shell enhances liposome stability against specific nanoparticle-induced damage.