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Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice
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Tetrahydrocannabinol (THC) intoxication in a toddler caused severe neurological symptoms, including seizures. This case highlights the critical need for parental education on safe storage to prevent accidental THC poisoning in children.

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Area of Science:

  • Pediatric Toxicology
  • Emergency Medicine
  • Childhood Neurological Emergencies

Background:

  • Unintentional poisoning is a significant risk for young children.
  • Tetrahydrocannabinol (THC) exposure can lead to severe health consequences in pediatric populations.
  • Normal developmental milestones do not preclude susceptibility to toxic exposures.

Observation:

  • A previously healthy 16-month-old child presented with altered consciousness, apnea, and status epilepticus.
  • Diagnostic workup excluded infection and trauma; head CT was normal.
  • Urine toxicology screen was positive for THC and negative for other substances.

Findings:

  • The clinical presentation was consistent with acute THC intoxication.
  • The severity of symptoms necessitated intubation and intensive care.
  • This case underscores the potential for serious neurological effects from pediatric THC exposure.

Implications:

  • Mandatory reporting and monitoring of THC intoxication in children are crucial for public health surveillance.
  • Effective parental education on the risks of unintentional THC poisoning is essential for prevention.
  • Implementing robust safeguarding measures is vital to protect young children from accidental exposure to THC-containing products.