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Post-infectious Irritable Bowel Syndrome: A Narrative Review
Anahita Sadeghi1, Mohammad Biglari2, Siavosh Nasseri Moghaddam1
1Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Middle East Journal of Digestive Diseases
|August 6, 2019
Summary
Post-infectious Irritable Bowel Syndrome (PI-IBS) can develop after infectious gastroenteritis, affecting 4-36% of patients. Current understanding of PI-IBS mechanisms and treatments remains limited, necessitating further research.
Area of Science:
- Gastroenterology
- Functional Gastrointestinal Disorders
Background:
- Irritable Bowel Syndrome (IBS) is a prevalent functional gastrointestinal disorder.
- Post-infectious IBS (PI-IBS) is a subtype triggered by infectious gastroenteritis.
- PI-IBS prevalence ranges from 4% to 36% in affected individuals.
Purpose of the Study:
- To review the latest advancements and challenges concerning PI-IBS.
- To discuss the diagnostic criteria and potential mechanisms of PI-IBS.
- To highlight the current lack of specific treatments for PI-IBS.
Main Methods:
- Literature review of recent studies on PI-IBS.
- Analysis of diagnostic criteria, including Rome IV.
- Discussion of etiological factors and host responses.
Main Results:
- PI-IBS is recognized as a distinct functional gastrointestinal disorder.
- The precise mechanisms underlying PI-IBS pathogenesis are not fully elucidated.
- No targeted therapies are currently established for PI-IBS management.
Conclusions:
- PI-IBS represents a significant clinical challenge within functional gastrointestinal disorders.
- Further research is crucial to understand PI-IBS etiology and develop effective treatments.
- The review underscores the need for novel therapeutic strategies for PI-IBS patients.
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