Discovery and Optimization of 2-Arylquinazolin-4-ones into a Potent and Selective Tankyrase Inhibitor Modulating Wnt

Hans-Peter Buchstaller1, Uwe Anlauf1, Dieter Dorsch1

  • 1Merck Healthcare KGaA , Global Research & Development , Frankfurter Strasse 250 , 64293 Darmstadt , Germany.

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