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New insight into transdermal drug delivery with supersaturated formulation based on co-amorphous system

Yuya Hirakawa1, Hiroshi Ueda2, Tetsuya Miyano2

  • 1Physicochemical and Preformulation, Applied Chemistry and Analysis, Research Laboratory for Development, Shionogi & Co., Ltd., 3-1-1, Futaba-cho, Toyonaka-shi, Osaka 561-0825, Japan; Department of Applied Chemistry, Graduate School of Engineering, Kyushu University, Motooka 744, Nishi-ku, Fukuoka 819-0395, Japan.

International Journal of Pharmaceutics
|August 6, 2019
PubMed

Keywords:
AtenololCo-amorphousIntermolecular interactionSupersaturationTransdermal drug deliveryUrea

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