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Published on: March 21, 2025
Infected Abdominal Aortic Aneurysm After Transrectal Ultrasound-Guided Biopsy of the Prostate: A Report of Two Cases
Haya Husam Al-Ani1, Manar Khashram1, Anastasia Dean1
1Department of Vascular Surgery, Auckland City Hospital, Auckland, New Zealand.
Abstract:
Primary infected abdominal aortic aneurysm (AAA) is an uncommon presentation which can be associated with significant morbidity and mortality. In this report, we present 2 cases of infected AAAs less than 10 days after a transrectal ultrasound-guided (TRUS) prostate biopsy. A 63-year-old male presenting with sepsis and back pain 9 days after TRUS biopsy was found to have a 27-mm ectatic abdominal aorta which expanded to 59 mm in the course of a week, despite antibiotic therapy. He underwent successful surgical excision of the infected aortic aneurysm and reconstruction using a vein. A 55-year-old male presented similarly, 7 days after prostate biopsy with a 60-mm aortic aneurysm. His aneurysm ruptured 2 days before planned intervention-he did not survive an emergency repair. In both cases, aortic tissue biopsies confirmed growth of Escherichia coli. Preexistence of an aortic aneurysm was not known in either case as neither patient had imaging of the abdominal aorta. We postulate the pathophysiology was due to hematogenous spread.
Insights
Primary infected abdominal aortic aneurysms (AAAs) are rare but serious complications following transrectal ultrasound-guided prostate biopsy. This report details two cases of Escherichia coli infection in AAAs shortly after biopsy, highlighting potential risks.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Urology
Background:
- Primary infected abdominal aortic aneurysm (AAA) is a rare but life-threatening condition.
- Transrectal ultrasound-guided (TRUS) prostate biopsy is an increasingly common urological procedure.
Observation:
- Two patients developed infected AAAs within 10 days of undergoing TRUS prostate biopsy.
- Both patients presented with sepsis and back pain, with rapid aneurysm expansion noted in one case.
- Aortic tissue biopsies confirmed Escherichia coli infection in both cases.
Findings:
- Infection of the abdominal aorta occurred shortly after prostate biopsy, suggesting a potential link.
- One patient survived surgical intervention, while the other succumbed to aneurysm rupture.
- Pre-existing, undiagnosed aortic aneurysms may be a risk factor for post-biopsy infection.
Implications:
- TRUS prostate biopsy may pose a risk for developing infected AAAs, particularly in patients with undiagnosed aneurysms.
- Early recognition and prompt management are crucial for improving outcomes in infected AAA cases.
- Further research is warranted to elucidate the pathophysiology and establish preventative strategies.
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