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Published on: December 6, 2016
Evaluation of Obstructive Sleep Apnea in Prone Versus Nonprone Body Positioning With Polysomnography in Infants With
Hanna Hong1, Choo Phei Wee2, Karla Haynes3
1Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, Children's Hospital Los Angeles, Los Angeles, CA, USA.
Insights
Prone positioning may improve obstructive sleep apnea in infants with Robin sequence, but does not fully resolve it. Objective evaluation is crucial for individual infant therapy decisions.
Area of Science:
- Pediatric Sleep Medicine
- Craniofacial Anomalies
- Respiratory Physiology
Background:
- Robin sequence (RS) management often involves prone positioning, posing a conflict with safe infant sleep guidelines.
- Obstructive sleep apnea (OSA) is a common complication in infants with RS.
Purpose of the Study:
- To evaluate the impact of prone versus nonprone sleep positioning on polysomnography (PSG) parameters in infants with RS.
- To determine if prone positioning improves OSA metrics in this population.
Main Methods:
- A pre-post interventional, nonblinded study design was employed.
- 11 infants with RS underwent polysomnography (PSG) with both nonprone and prone sleep positions.
- Key PSG parameters including obstructive apnea-hypopnea index (oAHI), central apnea index (CAI), sleep efficiency (SE), and arousal index (AI) were analyzed.
Main Results:
- Prone positioning showed a trend towards decreased median oAHI (16.0 to 14.0), CAI (2.9 to 1.0), and AI (28.0 to 19.9) (P = .065).
- Sleep efficiency (SE) increased from 67.4% to 85.2% (P = .227) in the prone position.
- While improvements were observed, complete resolution of obstruction was not achieved in any infant.
Conclusions:
- Prone positioning may offer benefits for some infants with Robin sequence experiencing obstructive sleep apnea.
- Therapeutic use of prone positioning requires careful, objective assessment for each infant.
- Further research may be needed to optimize positioning strategies for RS patients.
Objective:
Management of obstructive sleep apnea in infants with Robin sequence (RS) includes prone positioning during sleep, which conflicts with safe infant sleep data. We examined changes in polysomnography (PSG) parameters for prone versus nonprone body positions in these infants.
Design:
Pre-post interventional, nonblinded study.
Participants:
Infants with RS referred for PSG were recruited from craniofacial clinic and inpatient units at Children's Hospital Los Angeles, a tertiary pediatric center. Fourteen infants were recruited, and 12 studies were completed on both body positions; 11 studies were used in the analysis.
Interventions:
The PSG was divided into nonprone and prone sleep, moving from their usual sleep position to the other position midway in the study.
Main Outcome Measures:
Data was collected in each position for obstructive apnea-hypopnea index (oAHI), central apnea index (CAI), sleep efficiency (SE), and arousal index (AI). Signed rank test was used to evaluate the change in body position.
Results:
All infants were term except 1, age 7 to 218 days (mean: 55 days; standard deviation: 58 days), and 8 (57%) of 14 were female. From nonprone to prone sleep position, the median oAHI (16.0-14.0), CAI (2.9-1.0), and AI (28.0-19.9) decreased (P = .065); SE increased (67.4-85.2; P = .227).
Conclusions:
Prone positioning may benefit some infants with RS. However, even those with significant improvement in obstructive sleep apnea did not completely resolve their obstruction. The decision to use prone positioning as a therapy should be objectively evaluated in individual infants.
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