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Effects of LC-PUFA supply via complementary food on infant development-a food based intervention (RCT) embedded in a

Hermann Kalhoff1, Christina M Mesch2, Madlen Stimming2

  • 1Pediatric Clinic Dortmund, Dortmund, Germany. hermann.kalhoff@klinikumdo.de.

European Journal of Clinical Nutrition
|August 7, 2019
PubMed

Insights

Increased intake of long-chain polyunsaturated fatty acids (LC-PUFA) through complementary foods did not impact infant visual or cognitive development. This study found no significant differences in developmental outcomes between infants receiving fish or rapeseed oil and controls.

Area of Science:

  • Nutrition Science
  • Developmental Pediatrics
  • Public Health Nutrition

Background:

  • Infant long-chain polyunsaturated fatty acid (LC-PUFA) intake often declines with complementary feeding.
  • High LC-PUFA requirements persist for infant development during this period.

Purpose of the Study:

  • To investigate the impact of enhanced n-3 LC-PUFA intake via complementary foods on infant visual and cognitive development.
  • To assess if rapeseed oil or oily fish in complementary foods influences infant development.

Main Methods:

  • A randomized controlled trial involving mother-infant dyads.
  • Three groups: rapeseed oil, oily fish, and control (corn oil) in complementary foods from 5-10 months.
  • Evaluated visual development (FVEP) and cognitive/psychomotor development (Bayley's MDI/PDI).

Main Results:

  • No significant differences were observed in visual evoked potential (FVEP) latencies at 10 months.
  • Bayley's Mental Developmental Index (MDI) and Psychomotor Developmental Index (PDI) showed no significant group differences.
  • Neither fish nor rapeseed oil supplementation altered developmental outcomes.

Conclusions:

  • Complementary feeding with fish or rapeseed oil, within a structured diet, did not enhance visual or cognitive development in term infants.
  • Current infant feeding guidelines may not require specific LC-PUFA enrichment via these sources for optimal development.
Abstract

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