Related Experiment Video
Updated: Jan 21, 2026

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
Published on: June 14, 2017
Mitral stenosis produced by infective endocarditis involving a previously anatomically normal valve
Charles S Roberts1, Gregory P Milligan2, Robert C Stoler2
1Department of Cardiac Surgery, Baylor University Medical Center and the Baylor Scott & White Heart and Vascular HospitalDallasTexas.
A rare case of severe mitral stenosis resulted from methicillin-sensitive Staphylococcus aureus endocarditis on a normal mitral valve. This presentation of infective endocarditis causing significant valve stenosis is extremely uncommon.
Area of Science:
- Cardiology
- Infectious Diseases
- Valvular Heart Disease
Background:
- Infective endocarditis typically affects individuals with pre-existing valve abnormalities.
- Methicillin-sensitive Staphylococcus aureus (MSSA) is a common cause of endocarditis, but usually without severe valvular stenosis.
Observation:
- A 63-year-old male presented with symptoms attributed to a cardiac issue.
- Diagnostic evaluation revealed large vegetations on the mitral valve.
Findings:
- The patient was diagnosed with methicillin-sensitive Staphylococcus aureus endocarditis.
- The mitral valve vegetations were of a size that caused severe mitral stenosis.
- This etiology of valve stenosis, solely due to infective endocarditis on a normal valve, is exceptionally rare.
Implications:
- Highlights the potential for severe valvular dysfunction in infective endocarditis, even on previously normal valves.
- Underscores the importance of considering uncommon presentations of Staphylococcus aureus endocarditis.
- Suggests the need for vigilant monitoring and prompt intervention in cases of infective endocarditis to prevent irreversible valvular damage.
Related Concept Videos
Mitral Stenosis I: Introduction
Endocarditis II: Clinical Features of Infective Endocarditis
Mitral Valve Prolapse I: Introduction
Mitral Stenosis IV: Nursing Management
Mitral Stenosis III: Medical Management
Mitral Valve Prolapse II: Assessment and Management

