Multimodality depiction of findings in branchio-oto-renal syndrome: two case reports
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Updated: Jan 21, 2026

Multimodal Hierarchical Imaging of Serial Sections for Finding Specific Cellular Targets within Large Volumes
Published on: March 20, 2018
Lelia E Williams1, Mark T Sohner1, Robert C Sibley1
1Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Abstract:
Branchio-oto-renal syndrome is a rare genetic disorder that affects multiple organ systems. Temporal bone abnormalities include the unwound appearance of the cochlea which is common in this syndrome. This appearance can prompt renal imaging and evaluation. Presented here are two cases of branchio-oto-renal syndrome with dysplastic cochleae. A branchial cleft sinus and renal dysplasia were also present in one of the cases.
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