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Prenatal evaluation of the Sakoda complex
Usha D Nagaraj1,2, Rohitha Moudgal3, Robert J Hopkin3,4
1Department of Radiology and Medical Imaging, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave., Cincinnati, OH, 45229, USA. usha.nagaraj@cchmc.org.
Pediatric Radiology
|August 7, 2019
Summary
Sakoda complex, a rare birth defect, involves basal cephalocele, corpus callosum agenesis, and cleft lip/palate. This case highlights characteristic fetal MRI findings, crucial for prenatal diagnosis and management.
Area of Science:
- Medical Genetics
- Developmental Biology
- Pediatric Neurology
Background:
- Sakoda complex is a rare congenital disorder characterized by a specific triad of anomalies.
- Associated features include ophthalmologic, cognitive, and neurological deficits, notably severe epilepsy.
- Limited literature exists on prenatal imaging findings of this condition.
Observation:
- This report details a classic case of Sakoda complex in a child.
- Both prenatal (fetal) and postnatal Magnetic Resonance Imaging (MRI) findings are presented.
- The study emphasizes the characteristic features observed on fetal MRI.
Findings:
- The case presented classic Sakoda complex features on prenatal MRI.
- Prenatal imaging findings for Sakoda complex are described for the first time in the literature.
- Postnatal MRI confirmed the diagnosis and provided further anatomical detail.
Implications:
- Early and accurate diagnosis of Sakoda complex is critical.
- Prenatal diagnosis impacts counseling for expectant parents.
- Understanding these findings aids in planning perinatal management strategies.
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