Related Experiment Video

Updated: Jan 21, 2026

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.3K

Treatment of Pediatric Venous Thromboembolism

Katie A Meier1,2, Cristina Tarango1,3

  • 1Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Journal of Hospital Medicine
|August 7, 2019
PubMed

Insights

The 2018 American Society of Hematology guidelines offer evidence-based recommendations for treating pediatric venous thromboembolism. These guidelines aim to improve outcomes for children experiencing blood clots.

Area of Science:

  • Hematology
  • Pediatric Medicine
  • Clinical Guidelines

Background:

  • Venous thromboembolism (VTE) is a significant concern in children.
  • Effective management strategies are crucial for pediatric patients.

Purpose of the Study:

  • To provide comprehensive, evidence-based guidelines for the treatment of VTE in pediatric populations.
  • To standardize and improve the care of children with blood clots.

Main Methods:

  • Development by a multidisciplinary subcommittee of the American Society of Hematology.
  • Systematic review and synthesis of existing literature on pediatric VTE treatment.
  • Formulation of consensus-based recommendations.

Main Results:

  • Detailed recommendations on anticoagulation therapy, including agent selection and duration.
  • Guidance on managing specific VTE scenarios in children.
  • Considerations for long-term follow-up and prevention.

Conclusions:

  • The guidelines offer a framework for optimal VTE management in children.
  • Implementation aims to reduce morbidity and mortality associated with pediatric VTE.
  • These recommendations support evidence-based clinical decision-making.
Abstract

More Related Videos

A Patient-Derived Xenograft Model for Venous Malformation06:51

A Patient-Derived Xenograft Model for Venous Malformation

Published on: June 15, 2020

5.7K
Guidelines for Elective Pediatric Fiberoptic Intubation11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.4K

Related Concept Videos

Venous Return01:04

Venous Return

The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
11.8K
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
410
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
214
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
263
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
196
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
283