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Genotyping Single Nucleotide Polymorphisms in the Mitochondrial Genome by Pyrosequencing
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Genetics: Segregation of Mitochondrial Genomes in the Germline
1Departments of Neurology and Cell Biology, University of Miami Miller School of Medicine, Miami, FL, USA.
Current Biology : CB
|August 7, 2019
Abstract:
Mitochondrial genomes are present in hundreds of copies per cell. Recent work now reports the levels of inheritance of mtDNA heteroplasmy in humans and also explores mechanisms that restrict the inheritance of deleterious mtDNA variants in the Drosophila female germline.
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