Related Experiment Video
Updated: Jan 21, 2026

Author Spotlight: Establishing a New Fluorescence-Based Protocol for In Vivo Mitochondrial Morphology Analysis in Parkinson's Disease
Published on: June 23, 2023
Factors explaining physical activity level in Parkinson´s disease: A gender focus
Charlotte Urell1, Lena Zetterberg1, Karin Hellström1
1Department of Neuroscience, Physiotherapy, Uppsala University, Uppsala, Sweden.
Physical activity in Parkinson's disease (PD) is influenced by mobility, self-efficacy, and social support. Enjoyment is key for women, while self-efficacy is key for men with PD.
Area of Science:
- Neurology
- Gerontology
- Rehabilitation Science
Background:
- Parkinson's disease (PD) significantly impacts physical activity levels.
- Understanding factors influencing physical activity is crucial for managing PD.
- Gender differences in factors affecting physical activity in PD are not fully understood.
Purpose of the Study:
- To investigate the associations between self-rated physical activity and various factors in individuals with PD.
- To explore gender-specific relationships between these factors and physical activity levels.
Main Methods:
- A cross-sectional study involving 285 individuals with PD (mean age 69.1 years).
- Utilized validated self-reported scales for physical activity, self-efficacy, fall efficacy, social support, fatigue, and quality of life.
- Employed multiple regression analyses to identify significant predictors of physical activity.
Main Results:
- Physical activity levels were associated with mobility limitations, age, self-efficacy, communication, discomfort, social support, and time since diagnosis, explaining 54.5% of the variance.
- Enjoyment of physical activity was a significant predictor for women.
- Self-efficacy for physical activity was a significant predictor for men.
Conclusions:
- Interventions should focus on enhancing functional mobility, self-efficacy, social support, and enjoyment to promote physical activity in people with PD.
- Tailoring strategies based on gender may improve the effectiveness of physical activity interventions for individuals with PD.
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease: Overview
Factors Influencing Attraction II: Physical Attraction
Factors Affecting Activity Coefficient
The activity coefficient value for an ion is close to one when the solution has almost zero ionic strength, i.e., when the solution shows close to ideal behavior. As the ionic strength of the solution increases from 0 to 0.1 mol/L, a...
Socioemotional Experience and Gender Development
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...

