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Related Concept Videos

Peripheral Nervous System: Ganglia and Nerves01:24

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The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
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The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
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Spinal Nerves: Plexus II01:21

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The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
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Cranial Nerves: Types Part I01:14

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Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves, with the first six being essential in sensory perception, motor control, and autonomic functions related to the head and neck.
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Cranial Nerves: Types Part II01:22

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Cranial nerves are responsible for transmitting motor and sensory information between the brain and various parts of the body. There are twelve pairs of cranial nerves. While the first six innervate the head and neck, the latter six nerves innervate the head and neck, as well as organs and tissues in the thoracic and abdominal cavities. They facilitate communication, expression, and autonomic control within the human body.
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Spinal Nerves: Anatomy01:23

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Spinal nerves are pivotal conduits in the nervous system, bridging the central nervous system (CNS) with the peripheral nervous system (PNS). These nerves enable a complex communication network between the brain, spinal cord, and the rest of the body, facilitating sensory input, motor output, and autonomic functions.
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Related Experiment Video

Updated: Jan 21, 2026

Axoplasm Isolation from Rat Sciatic Nerve
05:29

Axoplasm Isolation from Rat Sciatic Nerve

Published on: September 24, 2010

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Peripheral nerve mucoid degeneration involving the sciatic nerve.

V P Fabbri1, A Valluzzi2, N Acciarri2

  • 1Unit of Anatomic Pathology, Department of Biomedical and Neuromotor Sciences, University of Bologna at Bellaria Hospital, Bologna, Italy.

Pathologica
|August 8, 2019
PubMed
Summary
This summary is machine-generated.

Peripheral nerve mucoid degeneration (PNMD) is a rare condition causing mucoid matrix buildup in nerves. This case report details PNMD in the sciatic nerve, covering its presentation, surgery, and pathology.

Keywords:
Peripheral nerve mucoid degenerationSciatic nerve

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Area of Science:

  • Neuropathology
  • Degenerative Diseases
  • Peripheral Nervous System Disorders

Background:

  • Peripheral nerve mucoid degeneration (PNMD) is an uncommon, non-neoplastic degenerative condition.
  • It is characterized by the accumulation of mucoid matrix within the endoneurium of peripheral nerves.

Observation:

  • This report presents a specific case of PNMD affecting the sciatic nerve.
  • Preoperative clinical and imaging features suggestive of PNMD are described.

Findings:

  • The case details the surgical intervention undertaken for the sciatic nerve involvement.
  • Pathological examination confirmed the endoneural mucoid matrix deposition characteristic of PNMD.

Implications:

  • This case contributes to understanding the clinical presentation and diagnostic features of PNMD.
  • It highlights the importance of considering PNMD in the differential diagnosis of sciatic nerve pathologies.
  • Further research may elucidate the pathogenesis and optimal management strategies for PNMD.