Imager-4D: New Software for Viewing Dynamic PET Scans and Extracting Radiomic Parameters from PET Data

Area of Science:

• Medical Imaging
• Radiochemistry
• Software Development

Background:

• Dynamic positron emission tomography (PET) imaging and radiomic feature extraction are areas of active research.
• Advanced analysis of dynamic PET data is crucial for improved diagnostic and prognostic capabilities.

Observation:

• A new software, Imager-4D, has been developed for viewing and analyzing dynamic PET data.
• The software is programmed in Java with FX extensions and is cross-platform compatible.
• It offers features for dynamic data analysis, quantitative metrics, and radiomic parameter extraction.

Findings:

• Imager-4D facilitates viewing and analysis of dynamic PET acquisitions, including dynamic whole-body imaging.
• The software supports various dynamic protocols, offers multiple display layouts, fused image display, and diverse volume-of-interest (VOI) selection methods.
• It enables quantitative analysis, including image summation and Patlak analysis, alongside radiomic feature extraction, termed 'dynomics'.

Implications:

• Imager-4D provides a user-friendly interface for deriving dynamic and radiomic parameters from PET data.
• The software's capabilities can streamline the process of obtaining standard PET parameters, dynamic data, and radiomic features.
• This tool has the potential to accelerate the integration of advanced dynamic PET data analysis into routine clinical practice.