Related Experiment Video
Updated: Jan 21, 2026

Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure
Published on: September 19, 2019
Interaction between vitamin A supplementation and chronic malnutrition on child development
Luciano Lima Correia1, Hermano Alexandre Lima Rocha1, Jocileide Sales Campos2
1Departamento de Saúde Comunitária, Faculdade de Medicina, Universidade Federal do Ceará. R. Prof. Costa Mendes 1608/5º, Rodolfo Teófilo. 60430-140 Fortaleza CE Brasil. correialuciano@hotmail.com.
Vitamin A supplementation benefits preschool children's development, but only if they have good nutritional status. Supplemented, well-nourished children showed reduced cognitive delay, unlike stunted children.
Area of Science:
- Child Development
- Nutritional Science
- Public Health
Background:
- Millions of preschool-aged children experience developmental delays.
- These delays are linked to various factors, including nutritional status.
- Vitamin A is crucial for child development.
Purpose of the Study:
- To investigate the association between vitamin A supplementation and improved child development.
- To explore the mediating role of nutritional status in this association.
Main Methods:
- A population-based study in Ceará, Brazil, included 8000 households and 1232 children aged 0-35 months.
- Child developmental status, nutritional determinants, and confounding factors were analyzed.
- Cox regression models evaluated main effects and interactions.
Main Results:
- Vitamin A supplementation demonstrated a protective effect against delays in cognitive and motor development.
- This effect was significantly modified by the child's nutritional status.
- Well-nourished children receiving supplementation had a 67% lower risk of cognitive delay; stunted children showed no benefit.
Conclusions:
- Vitamin A supplementation is effective in promoting child development.
- The benefits of supplementation are contingent upon adequate nutritional status.
- Combined strategies to improve nutrition and vitamin A intake are recommended for optimal child development.
More Related Videos
08:18Author Spotlight: Unraveling Vitamin A Transport Mechanisms — Linking Liver Receptors to Vision Health Through RBPR2 and RBP4 Interactions
Published on: October 4, 2024
07:27The Murine Choline-Deficient, Ethionine-Supplemented CDE Diet Model of Chronic Liver Injury
Published on: October 21, 2017
Related Concept Videos
Vitamins
Mineral, Vitamin and Water Absorption
Role of Skin in Vitamin D Synthesis
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
Role of Vitamins in Maintaining Bone Health
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Sustainable Development