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Qualitative Evidence Synthesis (QES) for Guidelines: Paper 3 - Using qualitative evidence syntheses to develop
Claire Glenton1, Simon Lewin1,2, Theresa A Lawrie3
1Norwegian Institute of Public Health, Oslo, Norway.
Health Research Policy and Systems
|August 9, 2019
Summary
Qualitative evidence syntheses (QES) enhance World Health Organization (WHO) guidelines by providing crucial implementation considerations. Further research is needed to refine how QES findings are integrated into guideline development and dissemination.
Area of Science:
- Health Systems Research
- Clinical Guideline Development
- Evidence Synthesis
Background:
- World Health Organization (WHO) aims to improve guideline methodology for transparency and evidence-based decision-making.
- Qualitative Evidence Syntheses (QES) are increasingly used alongside effectiveness data in WHO guidelines.
- QES provide insights into intervention acceptability, feasibility, and implementation considerations.
Purpose of the Study:
- To explore how findings from QES were used to develop implementation considerations for WHO guidelines.
- To reflect on methods and research implications for designing and utilizing QES in guideline development.
- To share experiences from WHO guideline technical teams that employed QES.
Main Methods:
- Convened a working group of technical teams involved in WHO guidelines (2010-2018) that used QES.
- Employed a pragmatic and iterative approach with stakeholder feedback.
- Discussed and identified key methods and research implications of QES in guideline development.
Main Results:
- QES gathered evidence on intervention acceptability, feasibility, equity, and outcome values.
- Synthesized qualitative evidence using standardized processes.
- Integrated QES findings with other information and expert input to identify implementation considerations.
Conclusions:
- QES are valuable for generating implementation considerations in guideline development.
- Further research is needed on integrating health systems frameworks, evidence confidence, and handling implementation challenges.
- Exploration of how QES findings can be incorporated into derivative products for implementation support is necessary.
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