Related Experiment Video
Updated: Jan 21, 2026

Simultaneous PET/MRI Imaging During Mouse Cerebral Hypoxia-ischemia
Published on: September 20, 2015
Variation in the use of MRI for cervical spine clearance: an opportunity to simultaneously improve clinical care and
Alia Albaghdadi1, Ira L Leeds1, Katherine L Florecki2
1Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
National guidelines for cervical spine clearance in trauma patients are not consistently followed. Significant variation exists in MRI use, influenced by hospital factors rather than patient injury severity.
Area of Science:
- Trauma Surgery
- Emergency Medicine
- Radiology
Background:
- Controversy exists regarding optimal cervical spine clearance in obtunded blunt trauma patients.
- Recent guidelines suggest MRI is not essential for collar clearance in this population.
- This study investigates national variations in MRI utilization and associated factors.
Purpose of the Study:
- To determine the extent of national variation in MRI use for cervical spine clearance.
- To identify patient-specific and hospital-specific factors influencing MRI practice.
Main Methods:
- Retrospective review of the National Trauma Data Bank (2007-2012).
- Inclusion of obtunded blunt trauma patients (GCS <8, AIS head >3, ventilated >72h) at Level 1 or 2 trauma centers.
- Multilevel modeling to analyze patient and hospital-level factors associated with spine MRI use.
Main Results:
- 32,125 patients from 395 trauma centers analyzed; mean MRI use was 9.9% (range 0.5%-68.7%).
- Younger patients and those with MVC/pedestrian injuries were more likely to receive MRI.
- Hospitals in the Northeast, Level 1 TCs, and non-teaching hospitals showed higher MRI utilization; ISS was not associated with MRI use.
Conclusions:
- Significant variation in MRI use persists, influenced by hospital characteristics (geography, level, teaching status) despite patient factors.
- Current national guidelines for limiting MRI in cervical spine evaluation are not consistently applied.
- Potential reasons include lack of physician awareness, institutional protocols, or clinical consensus.
Related Concept Videos
What is Variation?
The range, standard deviation, standard error, and variance are the different measures of variation.
Range: The range is the difference between its maximum and...
Decreased Body Temperature
Decreased pulse rate
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
Variation
When independent and dependent variables are plotted on a scatter plot, the slope of a line is a value that describes the rate of change between the two...
Hepatic Drug Clearance: Restrictive and Nonrestrictive Clearance
Most drugs undergo restrictive clearance, which is proportional to the...
Conservative Site-specific Recombination and Phase Variation
The recognition sites for Cre recombinase called LoxP...

