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The Open-Source Value Project enhances healthcare economic models using R for greater transparency and collaboration. Challenges include resource needs and integrating diverse feedback for improved value assessment.

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Area of Science:

  • Health economics
  • Computational modeling
  • Open-source software development

Background:

  • The Innovation and Value Initiative launched the Open-Source Value Project to boost credibility in model-based value assessment within the US healthcare system.
  • Open-source economic models are developed iteratively, incorporating public feedback to enhance relevance and transparency.

Purpose of the Study:

  • To describe the development experience of two Open-Source Value Project models: one for rheumatoid arthritis and one for EGFR-positive non-small-cell lung cancer.
  • To highlight the benefits and challenges of using an open-source, collaborative approach for economic model development in healthcare.

Main Methods:

  • Developed economic models using the R programming language, enabling advanced features like multiple model structures and individual patient simulations.
  • Utilized version control systems for managing source code changes, facilitating iterative and collaborative development.
  • Made models freely available to the public to ensure transparency and encourage collaboration.

Main Results:

  • Successfully developed and released open-source models for rheumatoid arthritis and non-small-cell lung cancer.
  • Identified challenges including increased resource requirements for multifaceted platforms and methodological hurdles in incorporating novel value elements.
  • Observed positive reception from the modeling community and patient organizations, contrasted with limited feedback from US decision-makers.

Conclusions:

  • Open-source model development offers significant potential for transparency and collaboration in healthcare value assessment.
  • Addressing resource demands and interdisciplinary communication challenges is crucial for the success of such initiatives.
  • Further engagement with US decision-makers is needed to fully realize the benefits of open-source economic modeling.