Tachycardia-induced cardiomyopathy in a patient with left-sided accessory pathway and left bundle branch block: A
Ioan Alexandru Minciuna1, Mihai Puiu, Gabriel Cismaru
15th Department of Internal Medicine, Cardiology-Rehabilitation, "Iuliu Hatieganu" Univerity of Medicine and Pharmacy Cluj-Napoca, Romania.
Insights
Tachycardia-induced cardiomyopathy (TIC) from atrioventricular reentrant tachycardia (AVRT) with left bundle branch block (LBBB) can be effectively treated with catheter ablation, restoring normal heart function. This intervention resolves heart failure symptoms and improves left ventricular ejection fraction.
Area of Science:
- Cardiology
- Electrophysiology
- Heart Failure Research
Background:
- Tachycardia-induced cardiomyopathy (TIC) results from prolonged elevated heart rates, causing reversible left ventricular dysfunction.
- Atrioventricular reentrant tachycardia (AVRT) is a frequent cause of TIC, often requiring catheter ablation for incessant forms.
- Left bundle branch block (LBBB) in AVRT complicates diagnosis and localization of accessory pathways (APs).
Observation:
- A 60-year-old woman presented with incessant palpitations and shortness of breath due to LBBB tachycardia causing hemodynamic instability.
- Echocardiography revealed global hypokinesia and a reduced left ventricular ejection fraction (LVEF) of 25%, leading to suspicion of TIC.
Findings:
- Electrophysiological study identified a left lateral accessory pathway.
- Successful catheter ablation of the AP at the lateral mitral ring was performed.
- Post-ablation, the patient's heart failure signs resolved, and LVEF normalized to 55% within one week.
Implications:
- AVRT with intrinsic LBBB is a rare but significant cause of TIC.
- Catheter ablation is the preferred treatment for AVRT-induced cardiomyopathy in patients with LBBB.
- Surface ECG analysis of QRS complex variations may aid in early diagnosis of ipsilateral APs in these complex cases.
Rationale:
Tachycardia-induced cardiomyopathy (TIC) is defined as systolic and/or diastolic dysfunction of the left ventricle resulting from prolonged elevated heart rates, completely reversible upon control of the arrhythmia. Atrioventricular reentrant tachycardia (AVRT) is one of the most frequent causes of TIC. In its incessant form, it is unlikely to be controlled by pharmacological treatment, catheter ablation being the principal therapeutic option. The coexistence of left bundle branch block (LBBB) in patients with AVRT may cause difficulties in the early diagnosis and management of tachycardia because of the wide complex morphology, making it harder to localize the accessory pathway (AP).
Patient Concerns:
A 60-year-old woman, presented incessant episodes of palpitations and shortness of breath due to a LBBB tachycardia leading to hemodynamic instability.
Diagnosis:
The patient had a wide QRS tachycardia, with LBBB morphology and a heart rate of 160/minute. Echocardiography showed global hypokinesia with 25% left ventricular ejection fraction (LVEF). Considering the patient's clinical picture, TIC was suspected.
Interventions:
The electrophysiological study revealed a left lateral accessory pathway. Catheter ablation was successfully performed at the level of the lateral mitral ring.
Outcomes:
One week after the ablation the patient had no signs of heart failure and the LVEF normalized to 55%. During 6-months follow-up the patient presented no more episodes of tachycardia or heart failure and the LVEF remained normal.
Lessons:
AVRT is rarely associated with intrinsic LBBB, being a potential cause of TIC. In these patients, it is unlikely to control the arrhythmia pharmacologically, catheter ablation being the best therapeutic option. The variation of QRS complex duration between LBBB pattern in SR and AVRT could be useful for early diagnosis of an ipsilateral AP on surface ECG.
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