Related Experiment Video
Updated: Jan 21, 2026
05:51
Digital-Droplet PCR to Detect Indels Mutations in Genetically Modified Anopheline Mosquito Populations
Published on: June 28, 2021
4.0K
G3viz: an R package to interactively visualize genetic mutation data using a lollipop-diagram
Xin Guo1,2,3, Bo Zhang1,2,3, Wenqi Zeng2,3
1School of Innovation and Entrepreneurship, Southern University of Science and Technology, Nanshan, Shenzhen 518055, China.
Bioinformatics (Oxford, England)
|August 9, 2019
Summary
g3viz is a new R package that simplifies visualizing genetic mutation data using interactive lollipop diagrams. This tool enhances cancer genomics research by offering an easy-to-use platform for exploring and annotating mutation effects.
Area of Science:
- Bioinformatics
- Computational Biology
- Cancer Genomics
Background:
- Lollipop diagrams are crucial for visualizing genetic mutation data in cancer genomics.
- Existing tools lack comprehensive functionality and ease of use for creating these diagrams.
Purpose of the Study:
- Introduce g3viz, an R package designed for interactive lollipop diagram visualization.
- Provide researchers with a user-friendly tool for exploring genetic mutation data.
Main Methods:
- Developed g3viz as an R package utilizing JavaScript for interactive web-based visualizations.
- Enabled users to generate high-quality figures through simple R code integration.
Main Results:
- g3viz allows interactive exploration of genetic mutation data via lollipop diagrams.
- Users can easily annotate findings and export high-quality figures.
Conclusions:
- g3viz offers a valuable and accessible tool for cancer genomics research.
- The package supports researchers with varying levels of bioinformatics expertise.
More Related Videos
Related Concept Videos
01:09Mutation, Gene Flow, and Genetic Drift
62.9K
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
62.9K
02:39Phase Diagrams
49.0K
A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...
49.0K
00:36Viral Mutations
39.8K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
39.8K
01:39Mutations
94.4K
Overview
94.4K
00:58DNA Packaging
112.1K
Overview
112.1K
01:32Chromatin Packaging
18.9K
Each human somatic cell contains 6 billion base pairs of DNA. Each base pair is 0.34 nm long, meaning each diploid cell contains a staggering 2 meters of DNA. This long DNA strand is packed inside a nucleus measuring only 10-20 microns in diameter with the help of specialized DNA-binding proteins called histones. Together they form a compact DNA-protein complex called chromatin. The chromatin is further compacted into higher-order structures. The highest level of compaction is achieved during...
18.9K