Related Experiment Video

Updated: Jan 21, 2026

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

11.6K

Factors influencing the end-diastolic vortex assessed by using vector flow mapping

Xiaoxia Zhang1, Jun Niu2, Ling Wu1

  • 1Postgraduate Training Base of Jinzhou Medical University, PLA 967th Hospital, Dalian, China.

Echocardiography (Mount Kisco, N.Y.)
|August 9, 2019
PubMed

Insights

Late diastolic vortex formation in the left ventricle (LV) is influenced by filling patterns and heart rate. Atrial contraction may enhance this vortex, improving diastolic-systolic coupling, especially in enlarged ventricles.

Area of Science:

  • Cardiovascular Physiology
  • Cardiac Imaging
  • Hemodynamics

Background:

  • The end-diastolic vortex plays a crucial role in left ventricular (LV) diastolic function.
  • Understanding factors influencing vortex dynamics is key to assessing cardiac health.

Purpose of the Study:

  • To investigate the determinants of the late diastolic vortex in normal and abnormal ventricles.
  • To analyze the relationship between vortex characteristics and hemodynamic parameters.

Main Methods:

  • Vector flow mapping analysis of Color Doppler data from the LV apical long-axis view.
  • Study included 57 patients with coronary artery disease, 57 with dilated cardiomyopathy, and 53 healthy volunteers.

Main Results:

  • In healthy individuals, vortex area and flux correlated with transmitral A velocity and heart rate.
  • Transmitral A velocity and heart rate were independent predictors of vortex flux.
  • LV size influenced vortex dynamics in patients with LV dysfunction and enlargement.

Conclusions:

  • Late LV filling significantly impacts end-diastolic vortex formation.
  • Compensatory atrial contraction can enhance the end-diastolic vortex, aiding diastolic-systolic coupling.
  • LV size is a critical factor affecting the end-diastolic vortex in pathological conditions.
Abstract

Keywords:
color Doppler flow imagingechocardiographyend-diastolevector flow mappingvortex

More Related Videos

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach07:49

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach

Published on: July 21, 2023

1.9K
Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis09:58

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis

Published on: June 27, 2020

3.1K

Related Concept Videos

Bioavailability: Influencing Factors01:22

Bioavailability: Influencing Factors

Bioavailability refers to the extent and rate at which a drug reaches systemic circulation in its active form. Extent refers to the amount of the drug that makes it into circulation, while rate is the speed at which it enters circulation. It is influenced by several factors critical for optimizing drug formulations, dosing regimens, and therapeutic outcomes.Physicochemical properties of drugs and formulationsThe solubility, stability, and dissolution rate of a drug significantly impact its...
351
Factors Influencing Microbial Growth: pH01:29

Factors Influencing Microbial Growth: pH

Microorganisms are classified as acidophiles, neutrophiles, or alkaliphiles based on their pH growth preferences, reflecting their adaptations to specific environments. Maintaining a stable intracellular pH is critical for macromolecular stability and enzymatic activity, which can be challenged by external pH variations.Neutrophiles, such as Escherichia coli, grow optimally between pH 5.5 and 8.0. These microorganisms inhabit neutral or slightly acidic environments and employ mechanisms like...
1.1K
Factors Influencing Attraction I: Proximity01:22

Factors Influencing Attraction I: Proximity

Proximity plays a fundamental role in shaping interpersonal attraction by increasing opportunities for interaction and fostering familiarity. Research consistently demonstrates that individuals are more likely to form social bonds with those who are physically closer to them, whether in residential settings, workplaces, or educational institutions. This effect is largely driven by the increased frequency of encounters, which facilitates the development of friendships and romantic...
247
Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
6.2K
Factors Influencing Bioavailability: First-Pass Elimination01:23

Factors Influencing Bioavailability: First-Pass Elimination

When a drug is taken orally, it undergoes a journey starting from the gastrointestinal (GI) tract, passing through the portal vein, reaching the liver, and finally entering the systemic circulation. This process involves the absorption of the drug across the GI tract. The liver is the primary site for metabolizing the drug, with some metabolism also occurring in the gut wall. This journey significantly reduces the quantity of the drug that reaches the systemic circulation, a phenomenon known as...
8.0K
Factors Influencing Microbial Growth: Temperature01:27

Factors Influencing Microbial Growth: Temperature

Microorganisms display remarkable adaptations, enabling them to thrive in diverse ecological niches across a wide range of temperatures. Temperature profoundly influences microbial growth by affecting enzymatic activity, membrane fluidity, and other cellular processes.Each microorganism operates within a specific temperature range defined by three cardinal points: minimum, optimum, and maximum. Below the minimum temperature, membranes lose fluidity, halting transport processes. Above the...
1.2K