Related Experiment Video
Updated: Jan 21, 2026

05:51
A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
26.4K
Twenty Years of Reflections in Mutation Research
1Department of Biology, College of the Holy Cross, One College Street, Worcester, MA 01610, USA.
Mutation Research. Reviews in Mutation Research
|August 10, 2019
Summary
This commentary reviews 44 papers from the Reflections series, exploring historical and philosophical aspects of mutation research. It highlights diverse topics and contributors, offering insights into the evolution of the field.
Area of Science:
- Genetics and Genomics
- History of Science
- Philosophy of Science
Background:
- Reflections series in Mutation Research Reviews, established in 1999.
- Focuses on historical and philosophical themes in mutation research.
- Covers interdisciplinary topics including sociology, politics, ethics, and history.
Purpose of the Study:
- To provide an editorial overview of the 44 papers published in the Reflections series.
- To reflect on the diverse contributors and the breadth of topics discussed.
- To synthesize the historical and philosophical contributions to mutation research.
Main Methods:
- Review and commentary on published papers.
- Analysis of contributor engagement and thematic content.
- Synthesis of historical and philosophical perspectives.
Main Results:
- The series has covered a wide range of mutation-related topics since 1999.
- Contributors represent diverse scientific and philosophical backgrounds.
- The papers collectively offer a rich historical and philosophical narrative of mutation research.
Conclusions:
- The Reflections series has significantly contributed to understanding the historical and philosophical dimensions of mutation.
- The interdisciplinary nature of the series enriches the discourse on mutation research.
- The series provides a valuable resource for researchers interested in the broader context of genetics and ethics.
Related Concept Videos
Mutations
94.4K
Overview
94.4K
Mutations
43.5K
Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
43.5K
Viral Mutations
39.7K
A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
39.7K
Reflection of Waves
4.5K
When a wave travels from one medium to another, it gets reflected at the boundary of the second medium. A common example of this is when a person yells at a distance from a cliff and hears the echo of their voice. The sound waves (longitudinal waves) traveling in the air are reflected from the bounding cliff. Similarly, flipping one end of a string whose other end is tied to a wall causes a pulse (transverse wave) to travel through the string, which gets reflected upon reaching the wall. In...
4.5K
Mutation, Gene Flow, and Genetic Drift
62.5K
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
62.5K
The Sense of Self: Reflected Self-Appraisal and Social Comparison
55.4K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
55.4K

