Related Experiment Video
Updated: Jan 21, 2026

Visualization of IL-22-expressing Lymphocytes Using Reporter Mice
Published on: January 25, 2017
Does It Matter if This Baby Is 22 or 23 Weeks?
Annie Janvier1,2, Trisha Prentice3, Jessica Wallace4
1Department of Pediatrics and Bureau de l'Éthique Clinique, Université de Montréal, Montréal, Canada.
This case study discusses the care of an extremely premature infant born at 22 weeks gestation. It highlights the ethical challenges and moral distress faced by healthcare professionals when providing intensive care for such vulnerable neonates.
Area of Science:
- Neonatology
- Perinatal Medicine
- Bioethics
Background:
- Extremely premature infants, defined as those born before 28 weeks of gestation, present significant challenges in neonatal intensive care.
- Outcomes for infants born at the threshold of viability, such as 22 weeks gestation, are historically poor, leading to complex ethical considerations.
- Previous outcomes at this specific neonatal intensive care unit (NICU) for 22-weekers were uniformly fatal, influencing staff perspectives.
Purpose of the Study:
- To describe the clinical course and management of a neonate born at 22 weeks and 6 days gestation.
- To explore the ethical dilemmas and moral distress experienced by healthcare providers when managing extremely premature infants.
- To examine the impact of parental decisions and institutional history on end-of-life care discussions in the NICU.
Main Methods:
- Case report of a single neonate born at 22 weeks and 6 days gestation.
- Review of clinical data including gestational age, birth weight, maternal prenatal care, and initial postnatal stability.
- Analysis of the ethical considerations and staff responses to the management of an extremely premature infant.
Main Results:
- The infant, weighing 530g, was born at 22 weeks and 6 days gestation and was initially stable on low ventilator settings with adequate blood pressure and urine output.
- Despite initial stability, the infant's extreme prematurity and the NICU's history of uniformly fatal outcomes for 22-weekers created significant moral distress among nursing staff.
- Parents, after counseling, opted for all available life-supporting measures, underscoring the complexities of shared decision-making in neonatal intensive care.
Conclusions:
- The management of infants born at the threshold of viability necessitates a careful balance between aggressive medical intervention and ethical considerations.
- Moral distress among healthcare professionals is a significant factor in the care of extremely premature neonates, influenced by patient outcomes and institutional history.
- Effective communication, parental counseling, and supportive care for healthcare teams are crucial when navigating the complexities of neonatal intensive care for extremely premature infants.
More Related Videos
Related Concept Videos
Classifying Matter by State
Classifying Matter by Composition
According to its composition, the matter can be classified into two broad categories — pure substances and mixtures.
A pure substance is a form of matter that has a constant composition throughout with uniform properties. For example, any sample of sucrose has the same composition and same physical properties, such as melting point, color, and sweetness, regardless of the source from which it is isolated.
A mixture is composed of two or...
Physical and Chemical Properties of Matter
The Atomic Theory of Matter
States of Matter
Scientists have discovered a fourth state of matter, plasma, that occurs naturally in the interiors...
What is Matter?

