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Waldenström Macroglobulinemia and Cerebral Venous Thrombosis: From Diagnosis to Complication

Paulo Zoé Costa1, Pedro Chorão2, Andreia Póvoa1

  • 1Department of Internal Medicine, Unidade Local de Saúde da Guarda E.P.E., Guarda 6301-857, Portugal.

Case Reports in Medicine
|August 10, 2019
PubMed

Waldenström macroglobulinemia (WM) is a type of non-Hodgkin lymphoma in which cancer cells produce large amounts of an abnormal protein that can cause hyperviscosity syndrome (HVS). A 43-year-old woman with WM, who developed seizures, had a head computed tomography scan that showed signs of cerebral venous thrombosis (CVT). Nevertheless, the value of immunoglobulin M was lower than 50 g/L, and evaluation of serum viscosity was not performed. Moreover, there was no history of bleeding, and the eye funduscopy was normal. These findings lead to think of causes of CVT other than HVS in a patient with WM.

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