Related Experiment Video
Updated: Jan 21, 2026

Recordings of Neural Circuit Activation in Freely Behaving Animals
Published on: July 22, 2009
Éloge de la Fuite: Neural Circuits for Avoiding Dangerous Situations
Ana González-Rueda1, Marco Tripodi1
1Neurobiology Division, Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
None:
When facing threats, animals not only innately freeze or flee, but can also learn to avoid harmful situations, a behaviour known as 'active avoidance'. A recent study by Hormigo et al. (J. Neurosci., 2019) provides new insights into the neural circuit responsible for this behaviour, placing the pedunculopontine tegmental nucleus (PPT) at its centre.
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