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Updated: Jan 21, 2026

Targeting the Rat's Small Bowel: Long-Term Infusion into the Superior Mesenteric Artery
Published on: April 8, 2021
Congenital superior mesenteric artery aneurysm in a 6-week-old infant presenting with upper gastrointestinal bleeding
Lakshmipriya Subbaraj1, Florencia Beleniski2, Jesse Courtier3
1Division of Pediatric Surgery, University of California, San Francisco, San Francisco, Calif.
Insights
Visceral artery aneurysms are rare in children. A congenital superior mesenteric artery aneurysm in an infant presenting with gastrointestinal bleeding was successfully treated with a stepwise surgical approach.
Area of Science:
- Pediatric surgery
- Vascular surgery
- Gastroenterology
Background:
- Visceral artery aneurysms (VAAs) are uncommon in pediatric populations, often linked to genetic conditions, trauma, or infections.
- While frequently asymptomatic, VAAs can lead to significant complications such as abdominal pain, nausea, vomiting, or life-threatening rupture.
- Rupture of VAAs may present as hemodynamic instability or gastrointestinal bleeding, requiring urgent intervention.
Observation:
- A rare case of a congenital idiopathic aneurysm of the superior mesenteric artery (SMA) was observed in a 6-week-old infant.
- The infant presented with significant gastrointestinal bleeding, indicating a critical complication of the SMA aneurysm.
- The case highlights the potential for rapid development of mesenteric collateral circulation in pediatric patients.
Findings:
- A stepwise surgical technique was employed to successfully exclude the superior mesenteric artery aneurysm and induce thrombosis.
- The surgical intervention effectively managed the gastrointestinal bleeding and stabilized the patient.
- Post-operative assessment confirmed the robustness of the mesenteric collateral circulation, crucial for maintaining visceral perfusion.
Implications:
- This case demonstrates a viable surgical strategy for managing pediatric visceral artery aneurysms, particularly SMA aneurysms.
- Highlights the importance of recognizing and promptly treating VAAs in infants to prevent catastrophic rupture.
- Emphasizes the adaptive capacity of mesenteric collateral circulation in children, which aids in surgical management and recovery.
Abstract:
Visceral artery aneurysms are rare in infants and children. The majority of cases are caused by genetic syndromes, trauma, or infection. Although the majority of aneurysms are asymptomatic, visceral artery aneurysms can present with abdominal pain, nausea/vomiting, or rupture. Aneurysm rupture can manifest as hemodynamic instability and/or gastrointestinal bleeding. We present the case of a congenital idiopathic aneurysm of the superior mesenteric artery in a 6-week-old infant who presented with gastrointestinal bleeding. We report a stepwise surgical approach to achieving aneurysm exclusion and thrombosis, and highlight the robust mesenteric collateral circulation that can develop in pediatric patients.
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