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In vivo Imaging of the Mouse Spinal Cord Using Two-photon Microscopy
Published on: January 5, 2012
Immunoglobulin G4-related disease involving both cerebral parenchyma and spinal cord: A case report
Jingfang Lin1, Linmao Zheng2, Dong Zhou1
1Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Abstract:
IgG4-related disease (IgG4-RD) is an immune-mediated condition that affects multiple organ systems with tumorlike swelling. Here, for the first time, we report a rare case of IgG4-RD that involves the cerebral parenchyma, intramedullary spinal cord and lymph nodes. The diagnosis of IgG4-RD was made based on histological features, multi organ involvement and high serum IgG4 levels. The patient responded well to glucocorticoid treatment. Our case broadens the phenotypic presentation for the neurological sequelae of IgG4-RD.
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