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Updated: Jan 21, 2026

Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model
Published on: November 4, 2021
Short and long-term outcomes of coronary perforation managed by coil embolization: A single-center experience
Qing Qin1, Shufu Chang1, Rende Xu1
1Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, NO 180, Fenglin Road, Shanghai 200032, China.
Insights
Coil embolization effectively manages coronary perforation during percutaneous coronary intervention (PCI), including complex chronic total occlusion (CTO) cases. This technique offers favorable short and long-term outcomes, facilitating successful revascularization.
Area of Science:
- Interventional Cardiology
- Vascular Surgery
- Medical Device Technology
Background:
- Coronary perforation is a significant complication during percutaneous coronary intervention (PCI).
- Effective management strategies are crucial for patient outcomes.
- Coil embolization has emerged as a potential treatment modality.
Purpose of the Study:
- To evaluate the short and long-term outcomes of patients with coronary perforation treated with coil embolization.
- To assess the efficacy of coil embolization in managing both distal and collateral coronary perforations.
- To determine the role of coil embolization in facilitating revascularization of chronic total occlusion (CTO) lesions.
Main Methods:
- Retrospective analysis of 66 patients undergoing PCI with coil embolization for coronary perforation (Oct 2012 - June 2018).
- Categorization of perforations into distal coronary and collateral types.
- Assessment of procedural success, complications, and follow-up outcomes including major adverse cardiac events.
Main Results:
- Coil embolization was used in 66 cases of coronary perforation (26 distal, 40 collateral).
- Successful revascularization was achieved in 72.2% of CTO cases using coil embolization.
- No deaths or myocardial infarctions were detected during a mean follow-up of 707 days, with only one late CABG in the collateral perforation group.
Conclusions:
- Coil embolization is a feasible and effective treatment for distal and collateral coronary perforations during PCI.
- This technique aids in the successful revascularization of complex CTO lesions.
- Coil embolization demonstrates favorable safety and efficacy in managing PCI-related coronary perforations.
Background:
Coronary perforation is a serious complication in percutaneous coronary intervention (PCI). In this article, we reported the short and long-term outcomes of patients with coronary perforation managed by coil embolization in our center.
Methods:
We retrospectively analyzed 66 patients who had coronary perforation treated by coil embolization during PCI performed in our center from Oct 2012 to June 2018.
Results:
Of sixty-six cases of coronary perforation, twenty-six cases were distal coronary perforation, while 40 cases were collateral perforation. The average coil number used in distal coronary and collateral perforation lesion is 1.8 ± 0.9 and 1.8 ± 1.0, respectively. The maximum number of coils implanted in each patient is 4 in both groups. Two emergency cardiac surgery to seal the perforation was performed after coil embolization in distal coronary perforation and pericardiocentesis. In collateral perforation, one case of CABG was performed due to myocardial ischemia caused by CTO lesion. During a follow-up of 707 ± 476 days, one patient in collateral perforation group had CABG one month later, while no death or myocardial infarction (MI) was detected. Fifty-four (81.2%) cases of perforations occurred while treating chronic total occlusion, and 74.0% of these perforations were located in collateral vessels, mostly epicardial vessels. Thirty-nine CTO cases (72.2%) were revascularized successfully with the aid of coil embolization.
Conclusion:
Coil embolization is feasible and effective in treating distal coronary perforation and collateral perforation during PCI procedure. In CTO lesions, coil embolization facilitates the success of revascularization by PCI.
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