Related Experiment Video
Updated: Jan 21, 2026
05:39
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
576
Systemic Lupus Erythematosus Presenting as Optic Neuropathy: A Case Report
1Internal Medicine, Hayatabad Medical Complex, Peshawar, PAK.
Cureus
|August 13, 2019
Summary
Optic neuritis, an uncommon initial symptom of Systemic Lupus Erythematosus (SLE), can cause vision loss. This case highlights optic neuropathy as the first sign of SLE in a 47-year-old woman.
Area of Science:
- Ophthalmology
- Rheumatology
- Immunology
Background:
- Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease.
- Optic nerve involvement, including optic neuritis, is a rare but possible manifestation of SLE.
- Early diagnosis of SLE is crucial for effective management and preventing organ damage.
Observation:
- A 47-year-old woman presented with left eye vision blurring and periorbital pain, indicative of optic neuritis.
- Associated symptoms included photosensitive rash, oral ulcers, and arthralgia, suggesting a systemic inflammatory process.
Findings:
- Ophthalmic examination revealed a relative afferent pupillary defect and bilateral arcuate visual field defects.
- Laboratory results showed positive antinuclear antibodies (ANA), anti-beta2-glycoprotein I, and low C4 complement levels, confirming SLE diagnosis.
Implications:
- This case highlights optic neuropathy as a potential initial presentation of SLE.
- Early recognition and diagnosis of SLE are vital for timely intervention and management of its diverse clinical manifestations.
Related Concept Videos
01:24Data Reporting and Recording
5.3K
Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.3K
01:25Types of Reports I: Hands-off Report
1.5K
A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
01:18Second Order systems II
390
In an underdamped second-order system, where the damping ratio ζ is between 0 and 1, a unit-step input results in a transfer function that, when transformed using the inverse Laplace method, reveals the output response. The output exhibits a damped sinusoidal oscillation, and the difference between the input and output is termed the error signal. This error signal also demonstrates damped oscillatory behavior. Eventually, as the system reaches a steady state, the error diminishes to zero.
390
01:21Types of Reports II: Incident or Occurrence Report
1.2K
An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K
01:21First Order Systems
402
First-order systems, such as RC circuits, are foundational in understanding dynamic systems due to their straightforward input-output relationship. Analyzing their responses to different input functions under zero initial conditions reveals significant insights into system behavior.
When a first-order system is subjected to a unit-step input, its response is characterized by its transfer function. By applying the Laplace transform of the unit-step input to the transfer function, expanding the...
When a first-order system is subjected to a unit-step input, its response is characterized by its transfer function. By applying the Laplace transform of the unit-step input to the transfer function, expanding the...
402
01:20Second Order systems I
575
A servo system exemplifies a second-order system, featuring a proportional controller and load elements that ensure the output position aligns with the input position. The relationship between these components is described by a second-order differential equation. Applying the Laplace transform under zero initial conditions yields the transfer function, showing how inputs are converted to outputs in the system.
By reinterpreting the system, one can derive the closed-loop transfer function, which...
By reinterpreting the system, one can derive the closed-loop transfer function, which...
575