Preliminary Analysis From the Craniofacial Collaboration United Kingdom Developmental Outcomes in Children With

Helen Care1, Patrick Kennedy-Williams1, Alexandra Cunliffe2

  • 1Oxford Craniofacial Unit, Oxford University Hospitals NHS Foundation Trust.

Insights

Most children with sagittal synostosis treated surgically show average development and behavior. However, parental concerns about conduct and hyperactivity were noted, suggesting potential issues as children age.

Area of Science:

  • Pediatric Surgery
  • Developmental Pediatrics
  • Craniofacial Surgery

Background:

  • The Craniofacial Collaboration United Kingdom (CC-UK) network was established in 2015.
  • This study analyzes the first wave of data from children aged 3 years with sagittal synostosis undergoing primary corrective surgery.

Purpose of the Study:

  • To assess developmental and behavioral outcomes in young children post-craniofacial surgery for sagittal synostosis.
  • To identify parental concerns regarding development and behavior in this cohort.

Main Methods:

  • Utilized a comprehensive and homogenous dataset from the CC-UK.
  • Collected parental measures of child development and behavior for 3-year-olds with treated sagittal synostosis.

Main Results:

  • The majority of children were rated by parents within one standard deviation of the mean for development and behavior.
  • Conduct and hyperactivity were areas of greatest parental concern, with 24% in the clinically significant range.
  • Significant differences in mean scores were observed between the sagittal synostosis group and normative data across 5 of 6 behavioral domains.

Conclusions:

  • While most children demonstrate average outcomes, a trend suggests potential for increased developmental difficulties with age.
  • Behavioral concerns, particularly conduct and hyperactivity, warrant further investigation.
  • Longitudinal research is needed to confirm findings and explore underlying mechanisms driving these outcomes.

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