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Focal seizure as a manifestation of serotonin syndrome: case report
Eyad Almallouhi1, Mohamad Rahwan1, Helen Dainton1
1Department of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA.
Abstract:
Serotonin syndrome is a life-threatening condition. Seizure is one of the complications of serotonin syndrome that may delay diagnosis and complicate management. We report a patient who had a focal seizure with abnormal electroencephalogram in the setting of serotonin syndrome with no prior history of epilepsy or seizure-provoking factors (fever, electrolyte abnormalities, specific medication combinations, and specific medication overdosing). Recognition of seizure as a symptom of serotonin syndrome is important for early treatment and avoidance of long-term consequences. Treatment of serotonin syndrome is mostly supportive. However, a short course of antiepileptics may be needed if these patients develop seizures.
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