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Optic Perineuritis in Neuromyelitis Optica Spectrum Disorder
Nur Afiah Kamaluddin1, Evelyn Tai1, Wan-Hazabbah Wan Hitam1
1Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, MYS.
Cureus
|August 13, 2019
Summary
Optic perineuritis, a rare demyelinating disease complication, was identified in a patient with neuromyelitis optica spectrum disorder. Early neuroimaging and immunosuppression are key for diagnosis and treatment.
Area of Science:
- Ophthalmology
- Neurology
- Immunology
Background:
- Optic perineuritis (OPN) is infrequently associated with demyelinating diseases.
- Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition affecting the optic nerves and spinal cord.
Observation:
- A case report details a young gentleman presenting with bilateral OPN.
- Initial misdiagnosis as a young stroke highlights diagnostic challenges.
Findings:
- This is the first reported instance of bilateral OPN linked to NMOSD.
- Diagnostic confirmation relied on distinguishing OPN from optic neuritis (ON) via early neuroimaging.
Implications:
- Highlights the importance of considering NMOSD in cases of OPN.
- Emphasizes the critical role of early neuroimaging in differentiating OPN and ON.
- Suggests systemic immunosuppression as the primary therapeutic strategy for NMOSD-associated OPN.
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