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Measurement of aflatoxin in Nigerian sera by enzyme-linked immunosorbent assay
D W Denning1, J K Onwubalili, A P Wilkinson
1Lister Unit, Northwick Park Hospital, Harrow Middlesex, UK.
Abstract:
Sera from 78 healthy men donating blood in Enugu, Nigeria were examined for aflatoxin by enzyme-linked immunosorbent assay (ELISA). Levels varied from less than 20 pg/ml to 3.1 ng/ml. The ELISA method is simple, sensitive and specific, and therefore well suited to the low-resource tropical environment. Aflatoxin is ingested in considerable amounts in Nigeria and many contribute, with hepatitis B, to the development of hepatocellular carcinoma.