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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
Left atrial size and volume in cats with primary cardiomyopathy with and without congestive heart failure
L Duler1, K F Scollan1, N L LeBlanc1
1Department of Clinical Sciences, Carlson College of Veterinary Medicine, Oregon State University, Corvallis, OR, 97331, USA.
Insights
In cats with heart disease, minimal left atrial size measurements, not volumes, best distinguish cardiomyopathy from congestive heart failure. Minimal LA size may be a better prognostic indicator for CHF in cats.
Area of Science:
- Veterinary Cardiology
- Echocardiography
- Feline Medicine
Background:
- Myocardial diseases are common acquired cardiac conditions in cats.
- These can lead to left atrial enlargement and congestive heart failure (CHF).
- Left atrial chamber quantification is crucial for diagnosis and prognosis.
Purpose of the Study:
- To compare two-dimensional linear measurements of left atrial (LA) size with two-dimensional LA volumes (LAV).
- To evaluate the effectiveness of these measurements in differentiating cardiac conditions in cats.
- To determine if LA volume calculations offer advantages over linear measurements in feline cardiology.
Main Methods:
- A retrospective study of 162 client-owned cats.
- Cats were categorized into healthy, cardiomyopathy (CM), or CHF groups.
- Seven LA size measurements were performed, including LA-to-aortic ratio (LA:Ao) and LAV.
Main Results:
- Minimal LA-to-aortic ratio (LA:Ao_min) and minimal LAV from the left apical view (LAV_min-LAP) best differentiated CM and CHF groups.
- An LA:Ao_min of 1.64 demonstrated optimal sensitivity (84%) and specificity (75%) for distinguishing CM and CHF.
- Minimal LA measurements showed a larger area under the curve compared to maximal values.
Conclusions:
- Left atrial volumes were not superior to linear measurements for distinguishing CM and CHF in cats.
- Minimal LA size and volumes performed better than maximal measurements.
- Minimal LA size may serve as a superior prognostic factor for CHF in cats with CM.
Introduction/Objectives:
Myocardial diseases are the most common acquired cardiac diseases in cats and may result in left atrial enlargement and congestive heart failure (CHF). Volume calculations have replaced linear measurements for chamber quantification in humans but are not commonly measured in cats. The aims of this retrospective study were to compare the left atrial (LA) size by two-dimensional linear measurements to two-dimensional LA volumes (LAV).
Animals:
One hundred sixty-two client-owned cats were included.
Materials And Methods:
Cats with complete echocardiographic examinations were included and categorized into one of the three groups: healthy, cardiomyopathy (CM), and CHF. Seven measurements of the LA size were performed including minimal and maximal LA-to-aortic ratio (LA:Ao) and LAV and also maximal left atrial diameter (LAD).
Results:
Cats were classified as healthy (n = 56), CM (n = 62), and CHF (n = 44). The minimal LA:Ao (LA:Aomin) and minimal LAV from the left apical view (LAVmin-LAP) best differentiated the CM and CHF groups. The LA:Aomin value with the optimal sensitivity and specificity to distinguish CM and CHF cats was 1.64 (sensitivity 84% and specificity 75%).
Conclusions:
Left atrial volumes were not superior to linear measurements of LA size in distinguishing CM and CHF cats in this study. Minimal LA size and volumes resulted in a larger area under the curve than each corresponding maximal value. Minimum LA size may be a better prognostic factor of CHF in cats with CM.
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