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Paediatric endophthalmitis: a UK retrospective study.

S Parvizi1,2, M Papadopoulos3, V Panteli4

  • 1Moorfields Eye Hospital, London, UK. sahar.parvizi@gmail.com.

Eye (London, England)
|August 14, 2019
PubMed
Summary
This summary is machine-generated.

Pediatric endophthalmitis, a severe eye infection after surgery, occurred in 0.17% of cases over 7 years. Previous glaucoma surgery was a key risk factor, necessitating an evidence-based treatment protocol for better outcomes.

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Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Infectious Diseases

Background:

  • Pediatric endophthalmitis is a rare but severe complication following intraocular surgery, trauma, or endogenous infections.
  • Prompt recognition and aggressive management are crucial due to the poor visual prognosis associated with this condition.

Purpose of the Study:

  • To determine the incidence and risk factors of exogenous endophthalmitis in children.
  • To develop an evidence-based protocol for the management of suspected exogenous endophthalmitis in pediatric patients.

Main Methods:

  • A retrospective review of aqueous and/or vitreous taps performed on children (≤18 years) from January 2009 to December 2016 was conducted.
  • Data from two tertiary referral hospitals were analyzed, including microbiology reports and patient case notes.

Main Results:

  • The incidence of postoperative endophthalmitis was 0.17% over the 7-year study period.
  • Eleven out of thirteen cases had a history of glaucoma procedures; Gram-positive bacteria were the most common isolates.
  • Poor visual outcomes (hand movement or worse) were observed in 9 out of 13 treated patients.

Conclusions:

  • Previous glaucoma surgery is identified as a significant long-term risk factor for pediatric endophthalmitis.
  • An evidence-based management protocol is proposed to improve treatment outcomes for this devastating condition.