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Nanosomal docetaxel lipid suspension based chemotherapy in a pregnant MBC patient - a case report

Rajkumar Ramaswamy1, Nisarg Joshi2, Mujtaba A Khan2

  • 1Department of Medical Oncology, Velammal Medical College and Research Institute, Madurai, Tamil Nadu 625009, India.

Oncotargets and Therapy
|August 14, 2019
PubMed

The current report presents a case of a pregnant woman with breast cancer metastasized to liver and lungs. The standard of care for breast cancer in pregnancy is anthracycline/taxane-based chemotherapy regimens. Docetaxel has shown a favorable toxicity profile during the second and third trimesters of pregnancy. A novel nanosomal docetaxel lipid suspension (NDLS) (DoceAqualip), with a proven efficacy and tolerability profile, has been approved in India for the treatment of advanced solid tumors since 2013. We present here a case of a pregnant woman with metastatic breast cancer managed with NDLS based TAC regimen showing a partial response after six cycles. The patient delivered a healthy male child with normal Apgar score and weight at the 32nd week of gestation.

Keywords:
DoceAqualipNDLSPABCbreast cancermetastaticpregnancy

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