Colon biopsies: benefit or burden?
Stefan Morarasu1,2,3, Muthana Haroon1, Bianca Codrina Morarasu1,2
1Naas General Hospital, Department of Surgery, Ireland.
Journal of Medicine and Life
|August 14, 2019
Summary
Random colon biopsies offer low diagnostic value, especially for diarrhea patients. Selective sampling during colonoscopy is recommended to avoid unnecessary medical system burden and improve diagnostic yield.
Area of Science:
- Gastroenterology
- Diagnostic procedures
- Histopathology
Background:
- Colonoscopy is a primary tool for diagnosing gastrointestinal diseases.
- Colon biopsy analysis is time-consuming and costly.
- Unnecessary biopsies strain medical resources.
Purpose of the Study:
- To analyze criteria for colon biopsies.
- To evaluate the diagnostic value of random colon sampling.
- To correlate findings in patients with diarrhea.
Main Methods:
- Retrospective analysis of 2109 colonoscopies over one year.
- Data collected from ENDORAD system.
- Descriptive statistical analysis.
Main Results:
- Only 7.4% of 496 random biopsies showed positive histology.
- Microscopic colitis found in 5.3% of diarrhea patients with normal colonoscopy.
- Diarrhea and age (under/over 60) correlated with random biopsy rates.
Conclusions:
- Random colon sampling has low diagnostic value.
- Biopsies should be selectively performed in specific patient groups.
- Targeted biopsies improve diagnostic efficiency and reduce healthcare costs.
Related Concept Videos
01:25Benefits of Self-Esteem
188
Self-esteem—an individual's overall evaluation of their worth—plays a complex role in psychological functioning and well-being. It is often associated with many positive traits, such as confidence, optimism, and perseverance. Individuals with high self-esteem typically experience better sleep, manage peer pressure more effectively, and report greater life satisfaction. Conversely, low self-esteem has been consistently linked with increased risks of depression, anxiety, and poor...
188
02:22The Colonization of Land
37.3K
Changes in the environment of the early Earth drove the evolution of organisms. As prokaryotic organisms in the oceans began to photosynthesize, they produced oxygen. Eventually, oxygen saturated the oceans and entered the air, resulting in an increase in atmospheric oxygen concentration, known as the oxygen revolution approximately 2.3 billion years ago. Therefore, organisms that could use oxygen for cellular respiration had an advantage. More than 1.5 years ago, eukaryotic cells and...
37.3K
00:58Symbiosis
36.9K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
36.9K
01:23Anatomy of the Intestines
86.9K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
86.9K
02:17Ecological Succession
21.3K
Ecological succession is influenced by the processes of facilitation, inhibition, and toleration. Facilitation occurs when early successional species create more favorable ecological conditions for subsequent species, such as enhanced nutrient, water, or light availability. In contrast, inhibition happens when early successional species create unfavorable ecological conditions for potential successive species, such as limiting resource availability. In some cases, later successional species...
21.3K
01:40Hormonal Regulation
47.8K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
47.8K