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Updated: Jan 21, 2026

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
A case report of right ventricular compression from a septal haematoma during retrograde coronary intervention to a
Darshan Doshi1, Raja Hatem2, Amirali Masoumi1
1Department of Medicine, Division of Cardiology, Columbia University Medical Center, 161 Ft. Washington Avenue, Herbert Irving Pavilion, 6th Floor, New York, NY, USA.
Background:
Septal haematomas causing left ventricular or biventricular outflow obstruction are rare but known complications of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) and can be life-threatening.
Case Summary:
In this case, we describe the formation of a septal haematoma during retrograde CTO PCI. The patient was initially managed conservatively but became progressively unstable, for which she underwent coiling of the inflow and outflow of the septal perforator. Despite coiling, she developed near complete right ventricular outflow obstruction (based on echocardiography). She was successfully managed with a percutaneous right ventricle assist device, with subsequent resolution of the outflow obstruction.
Discussion:
Septal haematomas with resultant outflow obstruction have been uniformly fatal. In our case, the use of a percutaneous right ventricle assist device was life-saving.
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