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Updated: Jan 21, 2026

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Published on: May 26, 2021
Atypical cutaneous targetoid lesions after bone marrow transplant
Connie S Zhong1,2, Edward T Richardson1,3, Alvaro C Laga Canales1,3
1Harvard Medical School, Boston, Massachusetts, USA.
Abstract:
A 69-year-old man with esophageal EBV-positive diffuse large B cell lymphoma status post allogeneic bone marrow transplant (BMT) five months prior presented to his oncologist with three days of maculopapular rash that was initially diagnosed as grade 1 graft-versus-host disease and started on oral prednisone. However, due to worsening of the rash, the patient presented to dermatology clinic, where skin biopsy revealed a diagnosis of erythema multiforme (EM). The patient improved with the use of topical steroids. This case highlights the atypical morphology of post-BMT EM and the potential causes for this atypical appearance.
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