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Identifying Suitable Target Regions and Analyzing Off-Target Effects of Therapeutic Oligonucleotides

Lykke Pedersen1, Peter H Hagedorn2, Troels Koch2

  • 1Therapeutic Modalities, Roche Pharma Research and Early Development, Roche Innovation Center Copenhagen, Hørsholm, Denmark. lykke.pedersen@roche.com.

Methods in Molecular Biology (Clifton, N.J.)
|August 15, 2019
PubMed

Keywords:
Antisense oligonucleotidesComputational predictionOff-target effectsRibonuclease HTarget regions

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